Project Director / PhD, Prof. Mechanisms of Inflammatory Diseases
Leo Joosten is as pathobiologist interested in host mechanisms that result in chronic inflammation. His recent research has focused on the role of cytokines in the pathogenesis of chronic inflammation and was aimed to find novel inhibitors to treat patients with inflammatory diseases. His research interests have also covered the contribution of pattern recognition receptors in the chronicity of inflammation. Current projects explore the role of immunometabolism and epigenetic reprogramming in the induction of innate immune memory or trained immunity. He is currently working on metabolic related diseases like gouty arthritis and associated hyperuricemia, type 2 diabetes and atherosclerosis, using research approaches based on primary human cells, murine models of infection and inflammation and human functional genomics. He is head of the laboratory of experimental medicine and staff member of the department of medicine at the Radboud UMC, Nijmegen, The Netherlands. He is also the group leader of our team working on the HINT project at the University of Medicine and Pharmacy in Cluj-Napoca.
The “Iuliu Hațieganu” University of Medicine and Pharmacy from Cluj-Napoca, Romania, Victor Babeș Street no. 8, PC 400023, as a beneficiary, announces the project titled: HINT „Hyperuricaemia – induced INflammation: Targeting the central role in rheumatic and cardiovascular diseases” approved for financing under the Competitiveness Operational Programme 2014-2020.
+40 748 862 518
+40 748 862 518
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